NF-kB p65/RelA Rabbit pAb (APR24831N)

pAbs-N

Calculated MW: 58kDa/59kDa/60kDaObserved MW: 65KDa

Recombinant fusion protein containing a sequence corresponding to amino acids 50-180 of human NF-kB p65/RelA (NP_068810.3).

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.

Affinity purification