Anti-Hsp70 Antibody (11096) - 100 µg

Antibody Products>Heat Shock and Stress Protein Antibodies|Products

Next Day 2 - 8°C

Hsp70 genes, members of a multigene family, encode heat-inducible 70kDa heatshock proteins that function as molecular chaperones. They have been identified in most organelles of eukaryotic cells as well as in bacteria. The N-terminus of Hsp70 binds ATP with high affinity and the C-terminus binds proteins and polypeptides. Hsp70s bind nascent polypeptides as well as partially folded intermediates of proteins, thus preventing their aggregation and/or misfolding. Binding of ATP triggers a conformational change that results in the release of bound protein. Hsp70s function in protein synthesis, protein folding and oligomerization, and protein transport.

PBS containing 0.1% sodium azide