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Anti-Human/Mouse Integrin β7 - Purified <i>in vivo </i>PLATINUM™ Functional Grade - 1 mg

Anti-Human/Mouse Integrin β7 - Purified <i>in vivo </i>PLATINUM™ Functional Grade - 1 mg

Item no.	LEIN-F2196-1mg
Manufacturer	Leinco Technologies
Amount	1 mg
Quantity options	100 mg 1 mg 25 mg 50 mg 5 mg
Category	In Vivo Antibodies Flow Cytometry
Type	Antibody Monoclonal
Applications	FC, other, IV
Clone	FIB27
Specific against	other
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Manufacturer - Applications	B, FC, in vivo
Manufacturer - Targets	Integrin Beta 7
Shipping Temperature	Next Day 2 - 8°C
Storage Conditions	Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at ≤ -70°C. Avoid Repeated Freeze Thaw Cycles.
Product Description	Integrin β7 is a 130 kD highly flexible membrane protein in the Ig superfamily that plays a role in lymphocyte adhesion. This flexibility facilitates a dynamic affinity for ligand via conformational changes. Integrin β7 forms heterodimers with α4 or αE (ITGAE) for structural stability. The α4/β7 heterodimer, also known as LPAM-1, binds to VCAM-1, MAdCAM-1 and fibronectin. The αE/β7 heterodimer interacts with E-Cadherin. Integrin β7 interacts with EED.
Concentration	≥ 5.0 mg/ml
Formulation	This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Antigen Distribution	Integrin β7 heterodimer α4/β7 is expressed on peripheral lymphocytes, thymocytes and bone marrow progenitors. Integrin β7 heterodimer αE/β7 is expressed on intestinal IEL, dendritic epidermal T cells, T regulatory cells, CD8+ T cells in lymph nodes and lamina propria.
Keywords	Monoclonal Antibody, integrin beta 7, β7 Integrin, integrin βp, ITGB7, FIB27, integrin β7, Mouse integrin β7, anti-human/mouse integrin β7 Antibody, Clone FIB27

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mg

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Delivery expected until 10/9/2025

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