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KDM5A-IN-1

KDM5A-IN-1

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	10mM/1mL
Item no.	HY-100014-10mM
Targets	Histone Demethylase
CASRN	1905481-36-8
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	KDM5A-IN-1 is a potent, orally bioavailable pan-histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 45 nM, 56 nM and 55 nM for KDM5A, KDM5B and KDM5C, respectively, and with an EC50 value of 960 nM for PC9 H3K4Me3. KDM5A-IN-1 is significantly less potent against other KDM5B enzymes (1A, 2B, 3B, 4C, 6A, 7B)[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	290.36
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : ≥ 50 mg/mL
Manufacturers Target	Histone Demethylase
Isoform	KDM5
Pathway	Epigenetics
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-100014-10mM-safety-datasheet.pdf