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AZD0156

AZD0156

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	50 mg
Item no.	HY-100016-50mg
Targets	ATR, ATM
CASRN	1821428-35-6
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	AZD0156 is a potent, selective and orally active ATM inhibitor with an IC50 of 0.58 nM. AZD0156 inhibits the ATM-mediated signaling, prevents DNA damage checkpoint activation, disrupts DNA damage repair, and induces tumor cell apoptosis[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	461.56
Clinical_Information	Phase 1
Manufacturers Research_Area	Cancer
Solubility	DMSO : 20 mg/mL (ultrasonic; adjust pH to 3 with HCl)
Isoform	ATM
Pathway	Apoptosis; Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-100016-50mg-safety-datasheet.pdf