« Back
Home /
Mitoquinone (mesylate)

Mitoquinone (mesylate)

Item no.	HY-100116A-10mM
Manufacturer	MedChem Express
CASRN	845959-50-4
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Oncology Metabolism Diabetes Glucose Homeostasis Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer Pancreatic Cancer
Type	Inhibitors
Specific against	other
Purity	99.09
Citations	[1]Mitchell T, et al. The mitochondria-targeted antioxidant mitoquinone protects against cold storage injury of renaltubular cells and rat kidneys. J Pharmacol Exp Ther. 2011 Mar;336(3):682-92.\|[2]Huang W, et al. Effects of the mitochondria-targeted antioxidant mitoquinone in murine acute pancreatitis. Mediators Inflamm. 2015;2015:901780. Acta Pharm Sin B. 2022 Feb;12(2):759-773. Acta Pharm Sin B. 2025 Apr;15(4):2095-2113. Acta Pharmacol Sin. 2022 Jan;43(1):177-193. Adv Sci (Weinh). 2024 Sep 20:e2404753. Aging Cell. 2021 Sep;20(9):e13468. Aging Cell. 2025 Oct 17:e70275. Am J Cancer Res. 2021 Mar 1;11(3):691-711. Anim Reprod Sci. 2025 May 14:278:107856. Antimicrob Agents Chemother. 2023 Jun 15;67(6):e0009823. Antioxidants (Basel). 2022 Apr 19;11(5):799. Antioxidants (Basel). 2024 Aug 19;13(8):1004. Autophagy. 2025 Oct 25. Biochem Biophys Res Commun. 2018 Sep 3;503(1):297-303. Biochem Pharmacol. 2025 Apr:234:116811. Biochim Biophys Acta Mol Cell Res. 2025 Dec;1872(8):120059. Biomaterials. 2023 Mar:294:121986. Biomed Pharmacother. 2025 Apr 28:187:118108. bioRxiv. 2024 August 06. bioRxiv. 2024 Mar 23. bioRxiv. 2025 July 21. bioRxiv. 2025 Sep 16. Brain. 2021 Nov 29;144(10):3126-3141. Cancer Lett. 2021 Aug 1:512:1-14. Cell Commun Signal. 2024 Nov 26;22(1):566. Cell Commun Signal. 2025 Sep 3;23(1):393. Cell Death Dis. 2021 Sep 8;12(9):839. Cell Death Dis. 2022 Jun 6;13(6):531. Cell Death Discov. 2025 Mar 1;11(1):82. Cell Metab. 2020 Dec 17;S1550-4131(20)30656-2. Cell Metab. 2023 Jan 3;35(1):200-211.e9. Cell Mol Neurobiol. 2025 May 29;45(1):53. Cell Rep. 2020 Nov 3;33(5):108340. Cell Rep. 2024 Dec 21;44(1):115094. Chem Biol Interact. 2025 Sep 26:111758. Chemosphere. 2023 May:323:138249. Commun Biol. 2022 Jul 22;5(1):726. Curr Biol. 2020 Sep 7;30(17):3378-3396.e7. Ecotoxicol Environ Saf. 2022 Jun 15;238:113595. Ecotoxicol Environ Saf. 2022 Mar 1:232:113219. Ecotoxicol Environ Saf. 2023 Oct 1:264:115409. EMBO J. 2023 Aug 15;42(16):e113258. EMBO Rep. 2021 May 5;22(5):e51532. EMBO Rep. 2023 Aug 3;24(8):e56635. EMBO Rep. 2024 Apr;25(4):2015-2044. Environ Health Perspect. 2024 Jun;132(6):67009. Environ Int. 2024 May 22:188:108771. Eur J Pharm Sci. 2023 Feb 1:181:106350. Eur J Pharmacol. 2024 Dec 15. Exp Cell Res. 2021 Dec 15;409(2):112934. Exp Gerontol. 2024 May:189:112401. Exp Mol Med. 2023 Mar;55(3):574-586. Fachbereich Biologie. 2020 Oct. Free Radic Biol Med. 2021 Apr:166:116-127. Free Radic Biol Med. 2024 Jul 9:S0891-5849(24)00552-5. Free Radic Biol Med. 2024 Mar:214:28-41. Free Radic Biol Med. 2024 Mar:214:54-68. Free Radic Biol Med. 2025 Oct:238:582-594. Immunology. 2024 Oct;173(2):339-359. Int Immunopharmacol. 2021 Jan;90:107149. Int Immunopharmacol. 2024 Jan 25:127:111328. Int J Mol Sci. 2023 May 24;24(11):9176. iScience. 2025 Feb 13;28(3):112020. J Agric Food Chem. 2021 Jul 14;69(27):7765-7776. J Agric Food Chem. 2025 Jul 2;73(26):16370-16383. J Cell Mol Med. 2024 May;28(9):e18353. J Dairy Sci. 2023 Oct;106(10):7266-7280. J Diabetes Investig. 2025 Nov 25. J Environ Manage. 2025 Apr:379:124775. J Equine Vet Sci. 2024 Aug 14:105168. J Ethnopharmacol. 2026 Feb 28:357:120941. J Exp Med. 2021 Sep 6;218(9):e20202637. J Inflamm Res. 2022 Aug 3:15:4409-4420. J Mol Cell Biol. 2023 Apr 20;14(12):mjac073. J Mol Neurosci. 2024 Mar 13;74(1):30. J Tradit Chinese Medical Sci. 2023 Feb 10. J Transl Med. 2025 Jan 8;23(1):30. Lat Am J Pharm. 2023 Feb 16; 42(1). mBio. 2025 Oct 8;16(10):e0218025. Mediators Inflamm. 2020 Aug 17;2020:3934769. Microchem J. 2024 Nov 28. Mol Ther. 2021 Dec 1;29(12):3498-3511. Nat Cell Biol. 2024 Sep;26(9):1545-1557. Nat Commun. 2022 Aug 6;13(1):4583. Nat Commun. 2023 Jul 24;14(1):4456. Nat Commun. 2025 Aug 12;16(1):7483. Nat Commun. 2025 Feb 18;16(1):1752. Nat Commun. 2025 Jun 2;16(1):5101. Nat Commun. 2025 May 8;16(1):4292. Neurotoxicology. 2023 Mar:95:155-163. Nucl Med Biol. 2025 Jan 22:142-143:108996. Oncogene. 2022 Jan;41(3):427-443. Oxid Med Cell Longev. 2021 Aug 13:2021:1394486. Oxid Med Cell Longev. 2021 Aug 31;2021:5608133. Oxid Med Cell Longev. 2022 Jun 1:2022:4290922. Oxid Med Cell Longev. 2022 Sep 20;2022:2213503. Patent. US20230088747A1. Pestic Biochem Physiol. 2025 May:210:106396. Phytother Res. 2024 Sep;38(9):4628-4649. PLoS One. 2021 Jan 12;16(1):e0245155. Proc Natl Acad Sci U S A. 2025 Nov 25;122(47):e2518190122. Redox Biol. 2020 Sep;36:101604. Redox Biol. 2021 Jul;43:101977. Redox Biol. 2021 May:41:101936. Redox Biol. 2021 Oct:46:102113. Redox Biol. 2022 Aug:54:102367. Redox Biol. 2022 Feb;49:102216. Redox Biol. 2024 Dec 3:79:103454. Redox Biol. 2025 Jun 9:85:103715. Research Square Preprint. 2021 Jul. Research Square Preprint. 2023 Jul 24. Research Square Preprint. 2023 Sep 1. Sci Rep. 2024 Oct 14;14(1):24044. Sci Rep. 2024 Sep 10;14(1):21154. Sci Total Environ. 2022 Mar 20:813:151899. SSRN. 16 Feb 2022. SSRN. 2023 May 22. SSRN. 2024 Jan 9. SSRN. 2025 Oct 19. SSRN. 2025 Sep 4. Toxicol Appl Pharmacol. 2023 Apr 15:465:116452. Toxicol In Vitro. 2022 Oct:84:105436. Toxicol In Vitro. 2023 Feb:86:105487. Toxicol Res (Camb). 2022 Sep 8;11(5):852-862. Toxicology. 2023 Mar 15:487:153466. Toxicology. 2024 May:504:153812. Acta Pharmacol Sin. 2024 Apr;45(4):777-789. Antioxidants (Basel). 2024 Jan 17;13(1):115. Biomed Pharmacother. 2020 Jun;126:110040. Biomed Pharmacother. 2023 Jun:162:114680. Chem Eng J. 2020 May. Free Radic Biol Med. 2024 Mar:213:79-89. Front Microbiol. 2023 Oct 31:14:1291358. J Exp Clin Cancer Res. 2020 Jun 23;39(1):119. J Neurosci Res. 2019 Dec;97(12):1689-1705. J Transl Med. 2022 May 14;20(1):222. Oxid Med Cell Longev. 2019 Dec 3;2019:5820415. Oxid Med Cell Longev. 2020 Mar 3;2020:2167129. Phytomedicine. 2025 Nov 25:148:157486. PLoS Pathog. 2023 May 8;19(5):e1011381. Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19635-19645. Toxicol Appl Pharmacol. 2019 May 1:370:78-92.
Smiles	[O-]S(=O)(C)=O.O=C(C(CCCCCCCCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)=C4C)C(OC)=C(OC)C4=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	MitoQ (mesylate),MitoQ10 (mesylate)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Category	Reference compound / Active compounds
Manufacturer - Targets	Reactive Oxygen Species (ROS)
Manufacturer - HS Code	H315, H317, H318, H334, H335, H341, H361, H370, H413
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, sealed storage, away from moisture)
Molecular Weight	678.81
Product Description	Mitoquinone mesylate is a TPP-based, mitochondrially targeted antioxidant in order to protect against oxidative damage[1].
Manufacturer - Research Area	Metabolic Disease; Cancer
Solubility	DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)\|Ethanol : 100 mg/mL (ultrasonic)\|H2O : 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Clinical information	Phase 4
UNSPSC Code	12352005
Precautionary	H315, H317, H318, H334, H335, H341, H361, H370, H413

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.