BAPTA

Item no.	HY-100168-500mg
Manufacturer	MedChem Express
CASRN	85233-19-8
Amount	500 mg
Quantity options	100 mg 10 mM/1 mL 200 mg 500 mg
Category	Cell Biology Cell Stainings Cardiovascular Research Ischemia & Reperfusion Injury Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.10
Citations	[1]R Y Tsien, et al. New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. Biochemistry. 1980 May 27;19(11):2396-404. \|[2]Roger C Hardie, et al. Inhibition of phospholipase C activity in Drosophila photoreceptors by 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid (BAPTA) and di-bromo BAPTA. Cell Calcium. 2005 Dec;38(6):547-56. \|[3]M B Collatz, et al. Intracellular calcium chelator BAPTA protects cells against toxic calcium overload but also alters physiological calcium responses. Cell Calcium Adv Sci (Weinh). 2021 May 27;e2100363.\|Aging. 2019 Nov 22;11(22):10385-10408.\|Biomed Pharmacother. 2023 Aug 25;166:115343.\|Biomed Pharmacother. 2023 May.\|bioRxiv. 2023 Jun 25.\|Cardiovasc Ther. 2023 Mar 30,22.\|Exp Neurol. 2023 Feb 13;363:114350.\|Free Radic Biol Med. 2024 Jan 6:S0891-5849(24)00002-9.\|J Cancer. 2024 Jan 1;15(2):343-355.\|J Cell Mol Med. 2020 Aug;24(16):9287-9299.\|J Clin Invest. 2024 Apr 25:e176355.\|J Ethnopharmacol. 2022: 115923.\|J Funct Foods. 2024 Oct.\|J Funct Foods. December 2021, 104791.\|J Ginseng Res. 10 August 2021.\|J Invest Dermatol. 2024 May 30:S0022-202X(24)00384-1.\|J Pharm Pharmacol. 2024 Jan 25:rgae002.\|J Pineal Res. 2024 Aug;76(5):e12987.\|J Thromb Haemost. 2021 Aug 19.\|Mil Med Res. 2023 Nov 25;10(1):56.\|Mol Med Rep. 2023 Nov 27.\|Sci Immunol. 2019 Jun 28;4(36):eaau6426.\|Sci Total Environ. 2020 Feb 10;703:134702.\|Toxicology. 2023 Nov 19:153674.\|Vet Microbiol. 2019 Dec;239:108498.\|Cell Signal. 2025 Mar 17:111753.
Smiles	O=C(O)CN(C1=CC=CC=C1OCCOC2=CC=CC=C2N(CC(O)=O)CC(O)=O)CC(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	85233-19-8
Shipping Condition	Room temperature
Available
Manufacturer - Type	Biochemical Assay Reagents
Manufacturer - Targets	Phospholipase
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	476.43
Product Description	BAPTA is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca2+ chelators[1][2].
Manufacturer - Research Area	Others
Solubility	1M NaOH: 33.33 mg/mL (ultrasonic; adjust pH to 11 with NaOH)\|DMSO: 15.62 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Metabolic Enzyme/Protease
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-100168-500mg-safety-datasheet.pdf