DSM265

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	25 mg
Item no.	HY-100184-25mg
Targets	Dihydroorotate Dehydrogenase; Parasite
CASRN	1282041-94-4
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	DSM265 is a long-duration inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 of 8.9 nM. DSM265 can also inhibit the growth of Pf3D7 parasites with an EC50 of 4.3 nM[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	415.33
Clinical_Information	Phase 2
Manufacturers Research_Area	Infection
Solubility	DMSO : 50 mg/mL (ultrasonic)\|Ethanol : 11.11 mg/mL (ultrasonic)
Manufacturers Target	Dihydroorotate Dehydrogenase; Parasite
Isoform	Plasmodium
Pathway	Anti-infection; Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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HY-100184-25mg-safety-datasheet.pdf