Comparison

SPDP European Partner

Item no. HY-100216-100mg
Manufacturer MedChem Express
CASRN 68181-17-9
Amount 100 mg
Quantity options 100 mg 10 mMx1 mL 10 mg 1 g 200 mg 250 mg 25 mg 500 mg 50 mg 5 g 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.14
Citations [1]Lobedanz S et al. A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug effluxpumps. Proc Natl Acad Sci U S A, 2007 Mar 13, 104(11):4612-7.|[2]Karumuthil-Melethil S et al. Dendritic cell-directed CTLA-4 engagement during pancreatic beta cell antigen presentation delays type 1diabetes. J Immunol 2010 Jun 15, 184(12):6695-708.
Smiles O=C(ON1C(CCC1=O)=O)CCSSC2=NC=CC=C2
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias SPDP Crosslinker,Py-ds-Prp-OSu
Shipping Condition Cool pack
Available
Manufacturer - Type
ADC Related
Manufacturer - Targets
ADC Linker
Shipping Temperature
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Molecular Weight
312.37
Product Description
SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1][2].
Manufacturer - Research Area
Cancer
Solubility
DMSO: 250 mg/mL (ultrasonic)
Manufacturer - Pathway
Antibody-drug Conjugate/ADC Related
Isoform
Cleavable Linker; Disulfide Cleavable Linker
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
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