Comparison

DREADD agonist 21 European Partner

Item no. HY-100234-10mM
Manufacturer MedChem Express
CASRN 56296-18-5
Amount 10 mM/1 mL
Quantity options 100 mg 10 mM/1 mL 10 mg 25 mg 2 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.46
Citations [1]Chen X, et al. The first structure-activity relationship studies for designer receptors exclusively activated by designer drugs. ACS Chem Neurosci. 2015 Mar 18;6(3):476-84.|[2]Thompson KJ, et al. DREADD Agonist 21 Is an Effective Agonist for Muscarinic-Based DREADDs in Vitro and in Vivo. ACS Pharmacol Transl Sci. 2018 Sep 14;1(1):61-72.
Smiles C12=CC=CC=C1NC3=CC=CC=C3C(N4CCNCC4)=N2
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 56296-18-5
Shipping Condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Neuroscience-Neuromodulation
Manufacturer - Targets
mAChR
Shipping Temperature
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight
278.35
Product Description
DREADD agonist 21 is a potent human muscarinic acetylcholine M3 receptors (hM3Dq) agonist (EC50=1.7 nM)[1].
Manufacturer - Research Area
Neurological Disease
Solubility
DMSO: ≥ 78 mg/mL
Manufacturer - Pathway
GPCR/G Protein; Neuronal Signaling
Isoform
mAChR3
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mM/1 mL
Available: In stock
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