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(-)-(S)-Equol

(-)-(S)-Equol

Item no.	HY-100583-25mg
Manufacturer	MedChem Express
CASRN	531-95-3
Amount	25 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer Testicular & Prostate Cancer
Type	Inhibitors
Specific against	other
Purity	99.68
Citations	[1]Setchell KD, et al. S-equol, a potent ligand for estrogen receptor beta, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora. Am J Clin Nutr. 2005 May;81(5):1072-9.\|[2]Lu Z, et al. S-equol, a Secondary Metabolite of Natural Anticancer Isoflavone Daidzein, Inhibits Prostate Cancer Growth In Vitro and In Vivo, Though Activating the Akt/FOXO3a Pathway. Curr Cancer Drug Targets. 2016;16(5):455-65.\|[3]Horiuchi H, et al. S-equol nantioselectively activates cAMP-protein kinase A signaling and reduces alloxan-induced cell death in INS-1 pancreatic β-cells. J Nutr Sci Vitaminol (Tokyo). 2014;60(4):291-6.
Smiles	OC1=CC=C2C[C@H](COC2=C1)C3=CC=C(C=C3)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	531-95-3
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	Endogenous Metabolite; Estrogen Receptor/ERR
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	242.27
Product Description	(-)-(S)-Equol is a high affinity ligand for estrogen receptor β with a Ki of 0.73 nM.
Manufacturer - Research Area	Cancer; Metabolic Disease; Neurological Disease
Solubility	DMSO: 100 mg/mL (ultrasonic; warming)
Manufacturer - Pathway	Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Isoform	Human Endogenous Metabolite
Clinical information	Phase 2

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HY-100583-25mg-safety-datasheet.pdf