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GS-444217

GS-444217

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	10mM/1mL
Item no.	HY-100844-10mM
Targets	MAP3K; Apoptosis
CASRN	1262041-49-5
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	GS-444217 is a potent, orally available and selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of 2.87 nM[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	411.46
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 15.5 mg/mL (ultrasonic; warming)
Manufacturers Target	Apoptosis; MAP3K
Isoform	MAP3K5/ASK1
Pathway	Apoptosis; MAPK/ERK Pathway
Manufacturers Product type	Reference compound

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HY-100844-10mM-safety-datasheet.pdf