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PAβN (dihydrochloride)

PAβN (dihydrochloride)

Item no.	HY-101444A-10mg
Manufacturer	MedChem Express
CASRN	100929-99-5
Amount	10 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 250 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.89
Citations	[1]Lomovskaya O, et al. Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy. Antimicrob Agents Chemother. 2001 Jan;45(1):105-16.\|[2]Kurin?i? M, et al. Effects of efflux pump inhibitors on erythromycin, ciprofloxacin, and tetracycline resistance in Campylobacter spp. isolates. Microb Drug Resist. 2012 Oct;18(5):492-501.\|[3]Lamers RP, et al. The efflux inhibitor phenylalanine-arginine beta-naphthylamide (PAβN) permeabilizes the outer membrane of gram-negative bacteria. PLoS One. 2013;8(3):e60666. bioRxiv. 2020 Apr.\|Front Cell Infect Microbiol. 2021 Mar 25;11:660431.\|Front Microbiol. 2024 Sep 24:15:1417237.\|J Antimicrob Chemother. 2021 Oct 11;dkab375.\|Microb Drug Resist. 2020 Jun;26(6):550-560.\|Microb Pathog. 2023 Oct 16:106397.\|mSphere. 2023 Feb 28;e0067322.\|World J Microbiol Biotechnol. 2024 Jun 6;40(8):233.\|ACS Infect Dis. 2024 Jan 5.\|Microbiol Spectr. 2023 Apr 18;e0308022.
Smiles	O=C([C@H](CCCNC(N)=N)NC([C@H](CC1=CC=CC=C1)N)=O)NC2=CC(C=CC=C3)=C3C=C2.Cl.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	MC-207,110 dihydrochloride,Phe-Arg-β-naphthylamide dihydrochloride
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Bacterial
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	519.47
Product Description	PAβN dihydrochloride (MC-207110 dihydrochloride) is an efflux pump inhibitor.
Manufacturer - Research Area	Infection
Solubility	DMSO: 83.33 mg/mL (ultrasonic)\|H2O: 14.29 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-101444A-10mg-safety-datasheet.pdf