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Siltenzepine

Siltenzepine

Item no.	HY-101694-10mg
Manufacturer	MedChem Express
CASRN	98374-54-0
Amount	10 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 20 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	[1]Pfeifer S, et al. Biotransformation und Pharmakokinetik von AWD 26-06, 8-Chlor-5,10-dihydro-5-[bis(2-hydroxyethyl)aminoacetyl]-11H- dibenzo[d,c][1,4]diazepin-11-on-hydrochlorid an der Ratte [Biotransformation and pharmacokinetics of AWD 26-06, 8-chloro-5,10-dihydro-5-[bis(2-hydroxyethyl)aminoacetyl]-11H-dibenzo[d, c][1,4]diazepin-11-one hydrochloride in the rat]. Pharmazie. 1990 Jul;45(8):603-7. German. [2]Trausch B, et al. The biliary and renal elimination of the new muscarinic-1-antagonist AWD 26-06 in volunteers with T-tube after cholecystectomy. Int J Clin Pharmacol Ther Toxicol. 1992 Nov;30(11):508-9.
Smiles	O=C1C2=CC=CC=C2N(C(CN(CCO)CCO)=O)C3=CC=C(Cl)C=C3N1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	AWD 26-06 (free base)
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	mAChR
Shipping Temperature	Room temperature
Molecular Weight	389.83
Product Description	Siltenzepine (AWD 26-06 free base) is an antagonist of mAChR with anti-acid activity, which can be used in peptic ulcers research. Siltenzepine exhibits rapidly but incompletely absorbed characterastic in rats (po)[1][2].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	10 mM in DMSO
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling
Clinical information	No Development Reported

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