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Acridine Orange (hydrochloride)

Acridine Orange (hydrochloride)

Item no.	HY-101879-100mg
Manufacturer	MedChem Express
CASRN	65-61-2
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Heart & Blood Cancer Bone Cancer
Type	Inhibitors
Specific against	other
Purity	99.86
Citations	[1]McMaster GK, et al. Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarosegels by using glyoxal and acridine orange. Proc Natl Acad Sci U S A. 1977 Nov;74(11):4835-8.\|[2]Traganos F, et al. Simultaneous staining of ribonucleic and deoxyribonucleic acids in unfixed cells using acridine orange in a flow cytofluorometric system. J Histochem Cytochem. 1977 Jan;25(1):46-56.\|[3]Byvaltsev VA, et al. Acridine Orange: A Review of Novel Applications for Surgical Cancer Imaging and Therapy. Front Oncol. 2019 Sep 24;9:925. \|[4]Wang Q, et al. Substrate stiffness regulates the differentiation profile and functions of osteoclasts via cytoskeletal arrangement. Cell Prolif. 2022 Jan;55(1):e13172. ACS Appl Mater Interfaces. 2025 Feb 5.\|Acta Pharm Sin B. 2021 Feb 11.\|Adv Funct Mater. 2023 Apr 14.\|Adv Sci (Weinh). 2024 Aug 9:e2404693.\|Cell Death Dis. 2020 Jul 30;11(7):607.\|Cell Death Dis. 2021 Jan 13;12(1):80.\|Cell Mol Immunol. 2025 Feb 5.\|Cell Prolif. 2021 Dec 24;e13172.\|Clin Transl Med. 2023 Mar;13(3):e1229.\|Environ Toxicol. 2023 May 20.\|Eur J Med Chem. 2024 Dec 5:279:116866.\|Eur J Med Chem. 2024 May 17:273:116507\|Free Radic Biol Med. 2023 Sep 1;208:402-417.\|Int J Mol Med. 2023 Apr 7.\|Int J Mol Sci. 2023 Sep 5, 24(18), 13812.\|Invest Ophthalmol Vis Sci. 2025 Feb 3;66(2):5.\|J Control Release. 2024 Oct 11:376:167-183.\|Microbiol Spectr. 2023 May 1;e0313822.\|Nat Commun. 2023 Jun 30;14(1):3877.\|Signal Transduct Target Ther. 2025 Mar 19.\|SSRN. 2023 Mar 9.\|SSRN. 2023 Nov 15.\|STAR Protoc. 2024 Sep 12;5(3):103309.\|Chemosphere. 2023 Apr;320:138071.\|Research Square Print. December 12th, 2022.
Smiles	CN(C)C1=CC=C2C(N=C3C=C(N(C)C)C=CC3=C2)=C1.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	65-61-2
Shipping Condition	Room temperature
Available
Manufacturer - Type	Dye Reagents
Manufacturer - Targets	DNA Stain; Fluorescent Dye; Parasite
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light, stored under nitrogen)
Molecular Weight	301.82
Product Description	Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm)[1][2][3].
Manufacturer - Research Area	Others
Solubility	DMSO: 25 mg/mL (ultrasonic)\|H2O: 50 mg/mL (ultrasonic; heat to 60°C)
Manufacturer - Pathway	Anti-infection; Cell Cycle/DNA Damage; Others
Clinical information	No Development Reported

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HY-101879-100mg-safety-datasheet.pdf