Comparison

LYN-1604 (hydrochloride) European Partner

Item no. HY-101923A-5mg
Manufacturer MedChem Express
CASRN 2216753-86-3
Amount 5 mg
Quantity options 100 mg 10 mM/1 mL 10 mg 1 ea 1 mg 25 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Citations [1]Zhang L, et al. Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo. Chem Sci. 2017 Apr 1;8(4):2687-2701.
Biochem J. 2019 Mar 12;476(5):875-887.|Cell Signal. 2024 Mar 11:118:111136.|Oxid Med Cell Longev. 15 Nov 2021.
Smiles ClC1=CC=C(C(CN2CCN(C(CN(CC(C)C)CC(C)C)=O)CC2)OCC3=CC=C(C=CC=C4)C4=C3)C(Cl)=C1.[H]Cl
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 2216753-86-3
Shipping Condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Cancer-Kinase/protease
Manufacturer - Targets
Apoptosis; Autophagy; ULK
Shipping Temperature
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight
621.08
Product Description
LYN-1604 hydrochloride is a potent UNC-51-like kinase 1 (ULK1) activator (EC50=18.94 nM) for the research of triple negative breast cancer (TNBC)[1].
Manufacturer - Research Area
Cancer
Solubility
DMSO : 100 mg/mL (ultrasonic)
Manufacturer - Pathway
Apoptosis; Autophagy
Isoform
ULK1
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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