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Dovitinib (lactate)

Dovitinib (lactate)

Manufacturer	MedChem Express
Category	Oncology Neuroscience Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Neural Signaling Inhibitors & Compound Libraries Small Molecules By Organ Head & Neck Cancer Heart & Blood Cancer
Type	Inhibitors
Specific against	other
Amount	10mM/1mL
Item no.	HY-10207-10mM
Targets	FLT3, KIT
CASRN	692737-80-7
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Dovitinib lactate (TKI258 lactate) is a multi-targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8/9, 10/13/8, 27/210 nM for FLT3, c-Kit, FGFR1/3, VEGFR1/2/3 and PDGFRα/β, respectively[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	482.51
Clinical_Information	Phase 3
Manufacturers Research_Area	Cancer
Solubility	DMSO : 25 mg/mL (ultrasonic)
Isoform	FGFR1; FGFR3; PDGFRα; PDGFRβ; VEGFR1/Flt-1; VEGFR2/KDR/Flk-1; VEGFR3/Flt-4
Pathway	Protein Tyrosine Kinase/RTK
Manufacturers Product type	Reference compound

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HY-10207-10mM-safety-datasheet.pdf