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AKT Kinase Inhibitor

AKT Kinase Inhibitor

Item no.	HY-10249A-10mM
Manufacturer	MedChem Express
CASRN	842148-40-7
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.92
Citations	[1]Saverio Alberti, et al. Use of trop-2 as predictive marker of response to anti-tumor therapy based on inhibitors of cd9, akt and molecules of the tetraspanin signalling network. WO2013171777A2. Cell Commun Signal. 2022 Mar 19;20(1):35.\|Cell Rep. 2023 May 23;42(6):112547.\|Cell Stem Cell. 2023 Apr 6;30(4):450-459.e9.\|Inflammation. 2021 Jan 5.\|Int J Biol Sci. 2024 Apr 29;20(7):2748-2762.\|J Cancer. 2021 May 5;12(13):3809-3818.\|Life Sci. 2019 Aug 15;231:116554. \|Mediat Inflamm. 2020 Jun 24;2020:3621261.\|Oxid Med Cell Longev. 2021 Mar 20.\|Pharmacol Res. 2024 May 18:107218.\|Phytother Res. 2022 Feb 17.\|Research Square Preprint. 2020 Dec.\|Research Square Preprint. 2023 May 26.\|Small. 2023 Jan 12;e2207194.\|Cell Death Dis. 2024 Nov 9;15(11):809.
Smiles	OCC#CC1=NC=C(C2=C1N=C(N2CC)C3=NON=C3N)OCCCN
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	842148-40-7
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	Akt
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	357.37
Product Description	AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 20 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	PI3K/Akt/mTOR
Clinical information	No Development Reported

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HY-10249A-10mM-safety-datasheet.pdf