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JNJ-7706621

JNJ-7706621

Manufacturer	MedChem Express
Category	Oncology Neuroscience Neural Lineage Markers Inhibitors & Compound Libraries Small Molecules By Organ Skin Cancer Bladder Cancer Head & Neck Cancer
Type	Inhibitors
Specific against	other
Amount	10mM/1mL
Item no.	HY-10329-10mM
Targets	Aurora Kinase; CDK; Apoptosis
CASRN	443797-96-4
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2, with IC50s of 9 nM, 3 nM, 11 nM, and 15 nM for CDK1, CDK2, aurora-A and aurora-B, respectively[1][2][3].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	394.36
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : ≥ 125 mg/mL
Manufacturers Target	Apoptosis; Aurora Kinase; CDK
Isoform	Aurora A; Aurora B; CDK1; CDK2; CDK3; CDK4; CDK6
Pathway	Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-10329-10mM-safety-datasheet.pdf