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Toceranib

Toceranib

Manufacturer	MedChem Express
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer
Type	Inhibitors
Specific against	other
Amount	10 mg
Quantity options	10mM*1 mL 10 mg 50 mg 5 mg
Item no.	HY-10330-10mg
Targets	KIT
CASRN	356068-94-5
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with Kis of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively. Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	396.46
Clinical_Information	Launched
Manufacturers Research_Area	Cancer
Solubility	DMSO : 2.5 mg/mL (ultrasonic)\|H2O : < 0.1 mg/mL
Isoform	PDGFRβ; VEGFR2/KDR/Flk-1
Manufacturers Pathway	Protein Tyrosine Kinase/RTK
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-10330-10mg-safety-datasheet.pdf