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(S,R,S)-AHPC-PEG6-C4-Cl

(S,R,S)-AHPC-PEG6-C4-Cl

Item no.	HY-103606-1g
Manufacturer	MedChem Express
CASRN	1835705-59-3
Amount	1 g
Quantity options	100 mg 1 g 2 g 500 mg 50 mg
Category	Oncology Neuroscience Protein Aggregation, Clearance & Misfolding Neural Development Inhibitors & Compound Libraries Small Molecules By Organ Colorectal Cancer Heart & Blood Cancer
Type	Inhibitors
Specific against	other
Purity	96.24
Citations	[1]Tovell H, et al. Rapid and Reversible Knockdown of Endogenously Tagged Endosomal Proteins via an Optimized HaloPROTAC Degrader. ACS Chem Biol. 2019 May 17;14(5):882-892.
Smiles	O=C([C@H]1N(C([C@H](C(C)(C)C)NC(COCCOCCOCCOCCOCCOCCCCCCCl)=O)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	VH032-PEG6-C4-Cl,VHL Ligand-Linker Conjugates 10,E3 ligase Ligand-Linker Conjugates 9
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	E3 Ligase Ligand-Linker Conjugates
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	827.47
Product Description	(S, R, S)-AHPC-PEG6-C4-Cl is a conjugate of ligands for E3 and 25-atom-length linker. The connector of linker is Halogen group. (S, R, S)-AHPC-PEG6-C4-Cl incorporates the (S, R, S)-AHPC based VHL ligand and 6-unit PEG linker. (S, R, S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO: ≥ 100 mg/mL\|Ethanol: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	PROTAC
Isoform	von Hippel-Lindau (VHL)
Clinical information	No Development Reported

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HY-103606-1g-safety-datasheet.pdf