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Flurbiprofen

Flurbiprofen

Item no.	HY-10582-500mg
Manufacturer	MedChem Express
CASRN	5104-49-4
Amount	500 mg
Quantity options	100 mg 10 mM/1 mL 1 g 500 mg
Category	Neuroscience Metabolism Cholesterol & Lipid Metabolism Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Enzymes Other Fatty Acid Enzymes Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.98
Citations	[1]Hosoi, T., et al., Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress. EMBO Mol Med, 2014.\|[2]Xiaobo Wang, et al. Flurbiprofen suppresses the inflammation, proliferation, invasion and migration of colorectal cancer cells via COX2. Oncol Lett. 2020 Nov; 20(5): 132.\|[3]E M Glenn, et al. The pharmacology of 2-(2-fluoro-4-biphenylyl)propionic acid (flurbiprofen). A potent non-steroidal anti-inflammatory drug. Agents Actions. 1973 Nov;3(4):210-6.
Smiles	FC1=C(C2=CC=CC=C2)C=CC(C(C)C(O)=O)=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	dl-Flurbiprofen
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-anti-virus
Manufacturer - Targets	Apoptosis; COX
Shipping Temperature	Room Temperature
Storage Conditions	Store at room temperature 3 years
Molecular Weight	244.26
Product Description	Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer[1][2][3].
Manufacturer - Research Area	Inflammation/Immunology; Cancer
Solubility	DMSO: ≥ 100 mg/mL
Manufacturer - Pathway	Apoptosis; Immunology/Inflammation
Isoform	COX; COX-1; COX-2
Clinical information	Launched

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HY-10582-500mg-safety-datasheet.pdf