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L-368,899 hydrochloride

L-368,899 hydrochloride

Item no.	HY-108677-5mg
Manufacturer	MedChem Express
CASRN	160312-62-9
Amount	5 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.78
Formula	C26H43ClN4O5S2
Citations	[1]Williams PD, et al. 1-((7,7-Dimethyl-2(S)-(2(S)-amino-4-(methylsulfonyl)butyramido)bicyclo [2.2.1]-heptan-1(S)-yl)methyl)sulfonyl)-4-(2-methylphenyl)piperaz ine (L-368,899): an orally bioavailable, non-peptide oxytocin antagonist with potential utility for managing preterm labor. J Med Chem. 1994 Mar 4;37(5):565-71. [2]Kathryn L. Thompson, et al. Pharmacokinetics and Disposition of the Oxytocin Receptor Antagonist L-368,899 in Rats and Dogs
Smiles	O=C(NC1[C@@](C2(C)C)(CS(=O)(N3CCN(C4=CC=CC=C4C)CC3)=O)CC[C@]2([H])C1)[C@H](N)CCS(=O)(C)=O.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	160312-62-9
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Targets	Oxytocin Receptor
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	591.23
Product Description	L-368, 899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC50s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively. L-368, 899 hydrochloride used as a tocolytic agent[1].
Manufacturer - Research Area	Endocrinology
Solubility	DMSO : 130 mg/mL (ultrasonic)\|H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	GPCR/G Protein
Clinical information	No Development Reported

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HY-108677-5mg-safety-datasheet.pdf