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KU-57788

KU-57788

Manufacturer	MedChem Express
Category	Oncology Neuroscience Neural Mitochondrial Function Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer
Type	Inhibitors
Specific against	other
Amount	10mM/1mL
Item no.	HY-11006-10mM
Targets	DNA-PK; CRISPR/Cas9
CASRN	503468-95-9
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	KU-57788 (NU7441) is a highly potent and selective DNA-PK inhibitor with an IC50 of 14 nM. KU-57788 is an NHEJ pathway inhibitor. KU-57788 also inhibits PI3K and mTOR with IC50s of 5.0 and 1.7 μM, respectively[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	413.49
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 14.29 mg/mL (ultrasonic)
Manufacturers Target	CRISPR/Cas9; DNA-PK
Pathway	Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-11006-10mM-safety-datasheet.pdf