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(Rac)-LM11A-31 (dihydrochloride)

(Rac)-LM11A-31 (dihydrochloride)

Item no.	HY-110155A-10mM
Manufacturer	MedChem Express
CASRN	1214672-15-7
Amount	10 mM/1 mL
Quantity options	10 mM/1 mL 10 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.0
Citations	[1]Elshaer SL, et al. Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinalvascular permeability in mice via inhibition of inflammation and the RhoA kinase pathway. Diabetologia. 2019 Aug;62(8):1488-1500.
Smiles	CCC(C)C(N)C(NCCN1CCOCC1)=O.[H]Cl.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1214672-15-7
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Drug Isomer
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, stored under nitrogen, away from moisture)
Molecular Weight	316.27
Product Description	(Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a non-peptide p75NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist[1].
Manufacturer - Research Area	Neurological Disease
Solubility	Ethanol: 100 mg/mL (ultrasonic)\|H2O: ≥ 125 mg/mL
Manufacturer - Pathway	Others
Clinical information	Phase 2

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HY-110155A-10mM-safety-datasheet.pdf