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EML 425

EML 425

Item no.	HY-110263-5mg
Manufacturer	MedChem Express
CASRN	1675821-32-5
Amount	5 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.04
Citations	[1]Milite C, et al. A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach. J Med Chem. 2015 Mar 26;58(6):2779-98.
Smiles	O=C(N(C(N(CC1=CC=CC=C1)C/2=O)=O)CC3=CC=CC=C3)C2=C/C4=C(C=C(O)C=C4C)C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1675821-32-5
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Epigenetic Reader Domain; Histone Acetyltransferase
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	440.49
Product Description	EML425 is a potent and selective CREB binding protein (CBP)/p300 inhibitor with IC50s of 2.9 and 1.1 μM, respectively.
Manufacturer - Research Area	Metabolic Disease; Neurological Disease; Cardiovascular Disease
Solubility	DMSO: ≥ 250 mg/mL
Manufacturer - Pathway	Epigenetics
Isoform	CBP/p300; TIP60
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-110263-5mg-safety-datasheet.pdf