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Homo-PROTAC cereblon degrader 1

Homo-PROTAC cereblon degrader 1

Item no.	HY-111594-5mg
Manufacturer	MedChem Express
CASRN	2244520-98-5
Amount	5 mg
Quantity options	100 mg 10 mMx1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Neuroscience Neural Development Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.66
Citations	[1]Steinebach C, et al. Homo-PROTACs for the Chemical Knockdown of Cereblon. ACS Chem Biol. 2018 Sep 21;13(9):2771-2782.
Smiles	O=C(N1C2CCC(NC2=O)=O)C3=CC=CC(NCCOCCOCCNC4=C5C(C(N(C6CCC(NC6=O)=O)C5=O)=O)=CC=C4)=C3C1=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	2244520-98-5
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	PROTACs
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, stored under nitrogen)
Molecular Weight	660.63
Product Description	Homo-PROTAC cereblon degrader 1 (compound 15a) is a highly potent and efficient Cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 200 mg/mL (ultrasonic)
Manufacturer - Pathway	PROTAC
Isoform	Cereblon
Clinical information	No Development Reported

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HY-111594-5mg-safety-datasheet.pdf