EX229

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	10mM/1mL
Item no.	HY-112769-10mM
Targets	AMPK
CASRN	1219739-36-2
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	EX229, a Benzimidazole derivative, is a potent and allosteric activator of AMP-activated protein kinase (AMPK), with Kds of 0.06 μM, 0.06 μM and 0.51 μM for α1β1γ1, α2β1γ1 and α1β2γ1 in biolayer interferometry, respectively.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-sugar/lipid metabolism
MolecularWeight	431.87
Clinical_Information	No Development Reported
Manufacturers Research_Area	Metabolic Disease
Solubility	DMSO : 13 mg/mL (ultrasonic; warming)
Manufacturers Target	AMPK
Isoform	AMPK α1β1γ1; AMPK α1β2γ1; AMPK α2β1γ1
Pathway	Epigenetics; PI3K/Akt/mTOR
Manufacturers Product type	Reference compound

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HY-112769-10mM-safety-datasheet.pdf