MW-150

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	10 mg
Item no.	HY-120111-10mg
Targets	p38 MAPK; Autophagy
CASRN	1628502-91-9
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	MW150 (MW01-18-150SRM) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM. MW-150 inhibits the ability of the endogenous p38α MAPK to phosphorylate an endogenous substrate MK2 in activated glia[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	381.47
Clinical_Information	Phase 2
Manufacturers Research_Area	Inflammation/Immunology; Neurological Disease
Solubility	DMSO : 40 mg/mL (ultrasonic)
Manufacturers Target	Autophagy; p38 MAPK
Isoform	p38α
Pathway	Autophagy; MAPK/ERK Pathway
Manufacturers Product type	Reference compound

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HY-120111-10mg-safety-datasheet.pdf