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trans-C75

trans-C75

Item no.	HY-12364A-10mg
Manufacturer	MedChem Express
CASRN	191282-48-1
Amount	10 mg
Quantity options	10 mM/1 mL 10 mg 1 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Lineage Markers Metabolism Cholesterol & Lipid Metabolism Enzymes Other Fatty Acid Enzymes Inhibitors & Compound Libraries Small Molecules By Organ Breast Cancer Testicular & Prostate Cancer Neuronal Cell Markers
Type	Inhibitors
Specific against	other
Purity	99.79
Citations	[1]Rae C, et al. Inhibition of Fatty Acid Synthase Sensitizes Prostate Cancer Cells to Radiotherapy.\|[2]Makowski K, et al. Differential pharmacologic properties of the two C75 enantiomers: (+)-C75 is a strong anorectic drug; (-)-C75 has antitumor activity. Chirality. 2013 May;25(5):281-7.\|[3]Gao S, et al. Effect of the anorectic fatty acid synthase inhibitor C75 on neuronal activity in the hypothalamus and brainstem. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5628-33.\|[4]Thupari JN, et al. C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9498-502.
Smiles	O=C([C@@H](C1=C)[C@@H](CCCCCCCC)OC1=O)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	(±)-C75
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Fatty Acid Synthase (FASN)
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	254.33
Product Description	trans-C75 ((±)-C75) is an enantiomer of C75. C75 is a synthetic fatty-acid synthase (FASN) inhibitor.
Manufacturer - Research Area	Cancer
Solubility	DMSO: 83.3 mg/mL (ultrasonic; warming)
Manufacturer - Pathway	Metabolic Enzyme/Protease
Clinical information	No Development Reported

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HY-12364A-10mg-safety-datasheet.pdf