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Stenoparib

Stenoparib

Manufacturer	MedChem Express
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Skin Cancer Breast Cancer Uterine, Ovarian & Cervical Cancer
Type	Inhibitors
Specific against	other
Amount	50 mg
Item no.	HY-12418-50mg
Targets	PARP
CASRN	1140964-99-3
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Stenoparib (E7449) is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ∼50 and ∼50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	317.34
Clinical_Information	Phase 2
Manufacturers Research_Area	Cancer
Solubility	DMSO : 6.4 mg/mL (ultrasonic; warming)
Manufacturers Target	PARP
Isoform	PARP1; PARP2; TNKS1/PARP5A; TNKS2/PARP5B
Pathway	Cell Cycle/DNA Damage; Epigenetics
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-12418-50mg-safety-datasheet.pdf