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Dantrolene (sodium hemiheptahydrate)

Dantrolene (sodium hemiheptahydrate)

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	100 mg
Item no.	HY-12542A-100mg
Targets	Calcium Channel; Autophagy
CASRN	24868-20-0
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Dantrolene sodium hemiheptahydrate is an orally active, non-competitive glutathione reductase inhibitor with a Ki of 111.6 μM and an IC50 of 52.3 μM. Dantrolene sodium hemiheptahydrate is a ryanodine receptor (RyR) antagonist and Ca2+ signaling stabilizer. Dantrolene sodium hemiheptahydrate is a direct-acting skeletal muscle relaxant. Dantrolene sodium hemiheptahydrate can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome[1][2][3].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
MolecularWeight	399.31
Clinical_Information	Launched
Manufacturers Research_Area	Others
Solubility	DMSO : ≥ 33 mg/mL\|H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target	Autophagy; Calcium Channel
Pathway	Autophagy; Membrane Transporter/Ion Channel; Neuronal Signaling
Manufacturers Product type	Reference compound

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HY-12542A-100mg-safety-datasheet.pdf