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FASN-IN-4

FASN-IN-4

Item no.	HY-12648-10mg
Manufacturer	MedChem Express
CASRN	1375105-96-6
Amount	10 mg
Quantity options	10 mM/1 mL 10 mg 2 mg 50 mg 5 mg
Category	Metabolism Cholesterol & Lipid Metabolism Enzymes Other Fatty Acid Enzymes Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.21
Citations	[1]Nicholas D. Adams, et al. Fatty acid synthase inhibitors. WO2012064642A1.\|[2]Junjun Chu, et al. Pharmacological inhibition of fatty acid synthesis blocks SARS-CoV-2 replication. Nat Metab. 2021 Nov;3(11):1466-1475. Cell Biosci. 2022 Sep 16;12(1):158.\|Nat Metab. 2021 Sep 27;1-10.\|Sci China Life Sci. 2021 May 27;1-21.
Smiles	O=C1COC2(CCN(S(=O)(C3=CC=C(C4=CC=C5C=CC=NC5=C4)C=C3)=O)CC2)CN1C6CC6
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1375105-96-6
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Fatty Acid Synthase (FASN); SARS-CoV
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	477.58
Product Description	FASN-IN-4 is a potent inhibitor of fatty acid synthase (FASN) with an IC50 of 10 nM (WO2012064642A1, compound 29)[1]. FASN-IN-4 also inhibits SARS-CoV-2 with an EC50 of 18.6 nM[2].
Manufacturer - Research Area	Infection; Metabolic Disease
Solubility	10 mM in DMSO
Manufacturer - Pathway	Anti-infection; Metabolic Enzyme/Protease
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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