Y16

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	5 mg
Item no.	HY-12649-5mg
Targets	Ras
CASRN	429653-73-6
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Y16 is a specific inhibitor of Leukemia-associated Rho guanine nucleotide exchange factor (LARG) with a Kd value of 76 nM. Y16 is active in blocking the interaction of LARG and related G-protein-coupled Rho GEFs with RhoA. Y16 shows no detectable effect on other diffuse B-cell lymphoma (Dbl) family Rho GEFs, Rho effectors, or a RhoGAP[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	384.43
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 25 mg/mL (ultrasonic)
Manufacturers Target	Ras
Pathway	GPCR/G Protein; MAPK/ERK Pathway
Manufacturers Product type	Reference compound

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HY-12649-5mg-safety-datasheet.pdf