LX7101

Manufacturer	MedChem Express
Category	Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	10mM/1mL
Item no.	HY-12659-10mM
Targets	ROCK
CASRN	1192189-69-7
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	LX7101 is a potent inhibitor of LIMK and ROCK2 with IC50 values of 24, 1.6 and 10 nM for LIMK1, LIMK2 and ROCK2, respectively; also inhibits PKA with an IC50 less than 1 nM.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
MolecularWeight	451.52
Clinical_Information	Phase 2
Manufacturers Research_Area	Others
Solubility	DMSO : 150 mg/mL (ultrasonic)
Manufacturers Target	ROCK
Isoform	ROCK2
Pathway	Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad
Manufacturers Product type	Reference compound

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HY-12659-10mM-safety-datasheet.pdf