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Mitapivat

Mitapivat

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	10mM/1mL
Item no.	HY-12689-10mM
Targets	Pyruvate Kinase
CASRN	1260075-17-9
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Mitapivat (AG-348) is an orally active pyruvate kinase allosteric activator. Mitapivat increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes, shows the potential to restore the activity of PK (pyruvate kinase)-deficient glycolytic pathways. Mitapivat can be used in study of PK deficiency[1][2][3].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	450.55
Clinical_Information	Launched
Manufacturers Research_Area	Metabolic Disease
Solubility	DMSO : 20.83 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target	Pyruvate Kinase
Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-12689-10mM-safety-datasheet.pdf