DC_517

Item no.	HY-12747-5mg
Manufacturer	MedChem Express
CASRN	500017-70-9
Amount	5 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Neuroscience Neural Epigenetics Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.67
Citations	[1]Chen S, et al. Identifying novel selective non-nucleoside DNA methyltransferase 1 inhibitors through docking-based virtual screening. J Med Chem. 2014 Nov 13;57(21):9028-9041.
Smiles	OC(CNC(C)C)COC(CN1C(C=CC=C2)=C2C3=C1C=CC=C3)CN(C4=CC=CC=C45)C6=C5C=CC=C6
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	500017-70-9
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	DNA Methyltransferase
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	505.65
Product Description	DC_517 is a DNA methyltransferase 1 (DNMT1) inhibitor, with an IC50 and a Kd of 1.7 μM and 0.91 μM, respectively.
Manufacturer - Research Area	Cancer
Solubility	DMSO: ≥ 50 mg/mL
Manufacturer - Pathway	Epigenetics
Isoform	DNMT1
Clinical information	No Development Reported

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HY-12747-5mg-safety-datasheet.pdf