« Back
Home /
AF38469

AF38469

Item no.	HY-12802-100mg
Manufacturer	MedChem Express
CASRN	1531634-31-7
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.28
Citations	[1]Schroder TJ, et al. The identification of AF38469: an orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin. Bioorg Med Chem Lett. 2014 Jan 1;24(1):177-80.
Smiles	O=C(NC1=CC=CC(C)=N1)C2=CC=C(C(F)(F)F)C=C2C(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1531634-31-7
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Targets	Neurotensin Receptor
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	324.25
Product Description	AF38469 is a selective, orally bioavailable Sortilin inhibitor with an IC50 value of 330 nM.
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO: ≥ 43 mg/mL
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-12802-100mg-safety-datasheet.pdf