SIS3

Manufacturer	MedChem Express
Category	Oncology Neuroscience Neural Lineage Markers Inhibitors & Compound Libraries Small Molecules By Organ Colorectal Cancer Neurodegeneration Markers;Research Area Neural Signaling
Type	Inhibitors
Specific against	other
Amount	10mM/1mL
Item no.	HY-13013-10mM
Targets	TGF-beta/Smad
CASRN	521984-48-5
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	(E)-SIS3 is a potent and selective inhibitor of Smad3 with an IC50 of 3 μM for Smad3 phosphorylation. (E)-SIS3 inhibits the myofibroblast differentiation of fibroblasts by TGF-β1[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	489.99
Clinical_Information	No Development Reported
Manufacturers Research_Area	Inflammation/Immunology
Solubility	DMSO : 100 mg/mL (ultrasonic)\|H2O : 1 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target	TGF-beta/Smad
Pathway	Stem Cell/Wnt; TGF-beta/Smad
Manufacturers Product type	Reference compound

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HY-13013-10mM-safety-datasheet.pdf