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MRT67307

MRT67307

Manufacturer	MedChem Express
Category	Neuroscience Neuroinflammation Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Clone	N/A
Amount	50 mg
Item no.	HY-13018-50mg
Targets	IKK; ULK; Autophagy
CASRN	1190378-57-4
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	MRT67307 is a dual inhibitor of the IKKε and TBK-1 with IC50s of 160 and 19 nM, respectively[1]. MRT67307 also inhibits ULK1 and ULK2 with IC50s of 45 and 38 nM, respectively. MRT67307 also blocks autophagy in cells[2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	464.60
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer; Inflammation/Immunology
Solubility	DMSO : ≥ 100 mg/mL
Manufacturers Target	Autophagy; IKK; ULK
Isoform	IKKε; TBK1; ULK1; ULK2
Pathway	Autophagy; NF-κB
Manufacturers Product type	Reference compound

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HY-13018-50mg-safety-datasheet.pdf