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Fexagratinib

Fexagratinib

Item no.	HY-13330-100mg
Manufacturer	MedChem Express
CASRN	1035270-39-3
Amount	100 mg
Quantity options	100 mg 10mM/1mL 10 mg 200 mg 50 mg 5 mg
Category	Neuroscience Neural Lineage Markers Neural Adhesion Molecules Inhibitors & Compound Libraries Small Molecules Calcium Binding Protein Markers
Type	Inhibitors
Clone	N/A
Specific against	other
Purity	99.85
Formula	C26H33N5O3
Citations	[1]Gavine PR, et al. AZD4547: an orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family. Cancer Res, 2012, 72(8), 2045-2056.
Smiles	C[C@H](C1)N[C@@H](C)CN1C2=CC=C(C(NC3=NNC(CCC4=CC(OC)=CC(OC)=C4)=C3)=O)C=C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	AZD4547; ADSK091
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	FGFR
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	463.57
Product Description	Fexagratinib (AZD4547; ADSK091) is a potent inhibitor of the FGFR family with IC50s of 0.2 nM, 2.5 nM, 1.8 nM, and 165 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.
Manufacturer - Research Area	Cancer
Solubility	DMSO : 125 mg/mL (ultrasonic)
Manufacturer - Pathway	Protein Tyrosine Kinase/RTK
Isoform	FGFR1; FGFR2; FGFR3; FGFR4
Clinical information	Phase 3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-13330-100mg-safety-datasheet.pdf