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Gossypol

Gossypol

Item no.	HY-13407-100mg
Manufacturer	MedChem Express
CASRN	303-45-7
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 200 mg 500 mg 50 mg
Category	Oncology Neuroscience Metabolism Diabetes Glucose Homeostasis Neural Signaling Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer Colorectal Cancer Uterine, Ovarian & Cervical Cancer
Type	Inhibitors
Specific against	other
Purity	99.67
Citations	[1]Oliver CL, et al. In vitro effects of the BH3 mimetic, (-)-Gossypol, on head and neck squamous cell carcinoma cells. Clin Cancer Res. 2004 Nov 15;10(22):7757-63. Microb Pathog. 2024 Sep 21:106960.\|Transbound Emerg Dis. 2023 Nov 11.\|Clin Transl Med. 2021 Jun;11(6):e467.\|Patent. US20220162561A1.\|Nat Commun. 2023 Jun 10;14(1):3445.\|Patent. US20220162561A1.
Smiles	O=CC1=C(O)C(O)=C(C(C)C)C2=CC(C)=C(C3=C(C)C=C4C(C(C)C)=C(O)C(O)=C(C=O)C4=C3O)C(O)=C12
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	BL 193
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Bcl-2 Family
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	518.55
Product Description	Gossypol binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively.
Manufacturer - Research Area	Cancer
Solubility	DMSO: 33.33 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis
Isoform	Bcl-2; Bcl-xL
Clinical information	Launched

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-13407-100mg-safety-datasheet.pdf