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Dorsomorphin (dihydrochloride)

Dorsomorphin (dihydrochloride)

Manufacturer	MedChem Express
Category	Food Safety Mycotoxins Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Clone	N/A
Amount	10mM/1mL
Item no.	HY-13418-10mM
Targets	AMPK; TGF-β Receptor; Autophagy
CASRN	1219168-18-9
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Dorsomorphin (Compound C) dihydrochloride is a potent, selective and ATP-competitive AMPK inhibitor, with a Ki of 109 nM. Dorsomorphin dihydrochloride inhibits BMP pathway by targeting the type I receptors ALK2, ALK3, and ALK6. Dorsomorphin dihydrochloride can reverse autophagy activation and anti-inflammatory effect of Urolithin A (HY-100599).
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	472.41
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 5 mg/mL (ultrasonic)\|H2O : 100 mg/mL (ultrasonic)
Manufacturers Target	AMPK; Autophagy; Organoid; TGF-β Receptor
Isoform	ALK2; ALK3; ALK6; AMPK
Pathway	Autophagy; Epigenetics; PI3K/Akt/mTOR; Stem Cell/Wnt; TGF-beta/Smad
Manufacturers Product type	Reference compound

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HY-13418-10mM-safety-datasheet.pdf