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Dorsomorphin

Dorsomorphin

Manufacturer	MedChem Express
Category	Metabolism Obesity Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	5 mg
Item no.	HY-13418A-5mg
Targets	AMPK; TGF-β Receptor; Autophagy
CASRN	866405-64-3
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Dorsomorphin (Compound C) is a selective and ATP-competitive AMPK inhibitor (Ki=109 nM in the absence of AMP). Dorsomorphin (BML-275) selectively inhibits BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin can reverse autophagy activation and anti-inflammatory effect of Urolithin A (HY-100599)[1][2].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	399.49
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 33.33 mg/mL (ultrasonic; adjust pH to 2 with 1M HCl)
Manufacturers Target	AMPK; Autophagy; Organoid; TGF-β Receptor
Isoform	ALK2; ALK3; ALK6; AMPK
Pathway	Autophagy; Epigenetics; PI3K/Akt/mTOR; Stem Cell/Wnt; TGF-beta/Smad
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-13418A-5mg-safety-datasheet.pdf