M344

Item no.	HY-13506-10mM
Manufacturer	MedChem Express
CASRN	251456-60-7
Amount	10 mM/1 mL
Quantity options	10 mM/1 mL 10 mg 50 mg 5 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer Breast Cancer Uterine, Ovarian & Cervical Cancer
Type	Inhibitors
Specific against	other
Purity	99.76
Citations	[1]Jung M1, et al. Amide analogues of trichostatin A as inhibitors of histone deacetylase and inducers of terminal cell differentiation. J Med Chem. 1999 Nov 4;42(22):4669-79.\|[2]Weberpals JI, et al. The effect of the histone deacetylase inhibitor M344 on BRCA1 expression in breast and ovarian cancer cells. Cancer Cell Int. 2011 Aug 19;11(1):29.
Smiles	O=C(NCCCCCCC(NO)=O)C1=CC=C(N(C)C)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	D 237,MS 344
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	HDAC
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	307.39
Product Description	M344 (D 237) is an inhibitor of histone deacetylase (IC50=100 nM) and an inducer of terminal cell fifferentiation.
Manufacturer - Research Area	Cancer
Solubility	DMSO : ≥ 100 mg/mL
Manufacturer - Pathway	Cell Cycle/DNA Damage; Epigenetics
Clinical information	No Development Reported
Isoform	HDAC

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