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Abarelix

Abarelix

Item no.	HY-13534-50mg
Manufacturer	MedChem Express
CASRN	183552-38-7
Amount	50 mg
Quantity options	10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Oncology Food Safety Histamines Hormones Inhibitors & Compound Libraries Small Molecules By Organ Testicular & Prostate Cancer
Type	Inhibitors
Specific against	other
Purity	99.90
Citations	[1]Koechling W, et al. A novel GnRH antagonist, causes minimal histamine release compared with abarelix in an ex vivo model of human skin samples. Br J Clin Pharmacol. 2010 Oct;70(4):580-7.\|[2]Kirby RS, et al. Abarelix and other gonadotrophin-releasing hormone antagonists in prostate cancer. BJU Int. 2009 Dec;104(11):1580-4.\|[3]Debruyne F, et al. Abarelix for injectable suspension: first-in-class releasing hormone antagonist for prostate cancer. Future Oncol. 2006 Dec;2(6):677-96.
Smiles	C[C@H](C(N)=O)NC([C@H]1N(C([C@H](CCCCNC(C)C)NC([C@H](CC(C)C)NC([C@@H](CC(N)=O)NC([C@H](CC2=CC=C(C=C2)O)N(C([C@H](CO)NC([C@@H](CC3=CC=CN=C3)NC([C@@H](CC4=CC=C(Cl)C=C4)NC([C@@H](CC5=CC=C6C=CC=CC6=C5)NC(C)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)CCC1)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	R3827,PPI 149
Shipping Condition	Cool pack
Available
Manufacturer - Type	Peptides
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	GnRH Receptor
Shipping Temperature	Blue Ice
Storage Conditions	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Molecular Weight	1416.06
Product Description	Abarelix (R3827; PPI 149) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer treatment.
Manufacturer - Research Area	Cancer; Endocrinology
Solubility	H2O: 42 mg/mL (ultrasonic; warming)\|DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	GPCR/G Protein
Clinical information	Launched

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HY-13534-50mg-safety-datasheet.pdf