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Norepinephrine (hydrochloride)

Norepinephrine (hydrochloride)

Item no.	HY-13715A-500mg
Manufacturer	MedChem Express
CASRN	329-56-6
Amount	500 mg
Quantity options	100 mg 10 mM/1 mL 1 g 500 mg 5 g
Category	Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.95
Citations	[1]MacGregor DA, et al. Relative efficacy and potency of beta-adrenoceptor agonists for generating cAMP in human lymphocytes. Chest. 1996 Jan;109(1):194-200.\|[2]Littlejohn NK, et al. Suppression of Resting Metabolism by the Angiotensin AT2 Receptor. Cell Rep. 2016 Aug 9;16(6):1548-60.\|[3]Brian P Ramos, et al. Adrenergic pharmacology and cognition: focus on the prefrontal cortex. Pharmacol Ther. 2007 Mar;113(3):523-36.\|[4]Xinyu Xu, et al. Binding pathway determines norepinephrine selectivity for the human β 1 AR over β 2 AR. Cell Res. 2021 May;31(5):569-579. Cardiovasc Res. 2018 Feb 1;114(2):300-311. \|Cell Biochem Funct. 2024 Jan 11.\|FASEB J. 2020 Nov;34(11):14892-14904.\|ACS Nano. 2022 Aug 23;16(8):12553-12568.\|Biochem Biophys Res Commun. 2023 Mar 24;657:108-118.\|bioRxiv. 2023 Oct 13.\|bioRxiv. 2024 July 31.\|bioRxiv. 2024 November 03.\|Cell Commun Signal. 2024 Jul 25;22(1):375.\|Cell Death Dis. 2020 Aug 18;11(8):644.\|Cell Mol Immunol. 2023 Jan 5.\|Cell Rep Med. 2023 May 24;101061.\|Eur J Pharmacol. 2022 May 12;175022.\|Food Science and Human Wellness. 2023 Nov;12(6);2061-2072.\|Gene. 2023 Aug 31;147753.\|Int J Mol Sci. 2022, 23(20), 12420.\|Int J Mol Sci. 2025 Mar 2;26(5):2243.\|J Am Heart Assoc. 2019 Jan 8;8(1):e009871.\|J Biol Chem. 2024 Oct 23:107924.\|J Cancer. 2024 Sep 9;15(17):5691-5709.\|J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Aug 15;1092:220-227.\|J Ethnopharmacol. 2024 Sep 26:118860.\|J Therm Biol. 2024 Jul 2:123:103906.\|Mol Cell Endocrinol. 2024 Nov 16:112417.\|Nat Commun. 2022 Jul 25;13(1):4278.\|Nat Commun. 2024 May 7;15(1):3834.\|Neurochem Int. 2020 Dec 16;104942.\|Ocul Immunol Inflamm. 2024 Dec 27:1-15.\|Sci Rep. 2022 Jun 15;12(1):9936.\|SSRN. 2023 May 8.\|Br J Pharmacol. 2020 Aug;177(15):3389-3402. \|Cell Rep. 2019 Dec 3;29(10):2936-2943.e4. \|J Nutr Biochem. 2018 May 1;58:110-118.\|Leiden University. Institute of Biology Leiden (IBL) , Faculty of Science.\|Nature. 2024 Dec 18.\|Neuroscience. 2019 Mar 1;401:59-72. \|Research Square Preprint. 2021 Aug.\|Theranostics. 2022 Jun 6;12(10):4718-4733.
Smiles	OC1=CC=C([C@@H](O)CN)C=C1O.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Levarterenol (hydrochloride),L-Noradrenaline (hydrochloride)
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	Adrenergic Receptor; Autophagy; Endogenous Metabolite
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	205.64
Product Description	Norepinephrine (Levarterenol; L-Noradrenaline) hydrochloride is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors[1][2][3][4].
Manufacturer - Research Area	Cardiovascular Disease; Endocrinology; Cancer
Solubility	DMSO: 44 mg/mL (ultrasonic)\|H2O: 250 mg/mL (ultrasonic)
Manufacturer - Pathway	Autophagy; GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Isoform	Human Endogenous Metabolite; Microbial Metabolite; α adrenergic receptor; β adrenergic receptor
Clinical information	Launched

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HY-13715A-500mg-safety-datasheet.pdf