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Sardomozide

Sardomozide

Item no.	HY-13746-10mg
Manufacturer	MedChem Express
CASRN	149400-88-4
Amount	10 mg
Quantity options	100 mg 10 mg 1 ea 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	SSRN. 2024 Mar 14. bioRxiv. 2024 August 26. Cell Rep. 2025 Jan 28;44(1):115123. Cell. 2020 Jun 11;181(6):1329-1345.e24. mSystems. 2024 Apr 2:e0024624. Sci Adv. 2023 May 19;9(20):eade0718. [1]Regenass U, et al. CGP 48664, a new S-adenosylmethionine decarboxylase inhibitor with broad spectrum antiproliferative and antitumor activity. Cancer Res. 1994 Jun 15;54(12):3210-7. [2]Kramer DL, et al. Lysosomal sequestration of polyamine analogues in Chinese hamster ovary cells resistant to the S-adenosylmethionine decarboxylase inhibitor, CGP-48664. Cancer Res. 1998 Sep 1;58(17):3883-90.
Smiles	N=C(C1=CC=CC2=C1CC/C2=N\NC(N)=N)N
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	CGP 48664,SAM-486A
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Others
Shipping Temperature	Room temperature
Molecular Weight	230.27
Product Description	Sardomozide is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM.
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Others
Clinical information	Phase 2

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