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Aripiprazole

Aripiprazole

Item no.	HY-14546-10mM
Manufacturer	MedChem Express
CASRN	129722-12-9
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 1 g 200 mg 500 mg 5 g
Category	Food Safety Histamines Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.95
Citations	[1]Stip E, et al. Aripiprazole in schizophrenia and schizoaffective disorder: A review. Clin Ther. 2010;32 Suppl 1:S3-20.\|[2]Burris KD, et al. Aripiprazole, a novel antipsychotic, is a high-affinity partial agonist at human dopamine D2 receptors. J Pharmacol Exp Ther. 2002 Jul;302(1):381-9.\|[3]Davies MA, et al. Aripiprazole: a novel atypical antipsychotic drug with a uniquely robust pharmacology. CNS Drug Rev. 2004 Winter;10(4):317-36.\|[4]Crespo-Facorro B, et al. Aripiprazole as a Candidate Treatment of COVID-19 Identified Through Genomic Analysis. Front Pharmacol. 2021 Mar 2;12:646701.\|[5]Russo E, et al. Ameliorating effects of aripiprazole on cognitive functions and depressive-like behavior in a genetic rat model of absence epilepsy and mild-depression comorbidity. Neuropharmacology. 2013 Jan;64:371-9.
Smiles	O=C1NC2=C(C=CC(OCCCCN3CCN(C4=CC=CC(Cl)=C4Cl)CC3)=C2)CC1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	OPC-14597
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	5-HT Receptor; Dopamine Receptor
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	448.39
Product Description	Aripiprazole (OPC-14597), an atypical antipsychotic, is a potent and high-affinity dopamine D2 receptor partial agonist. Aripiprazole is an inverse agonist at 5-HT2B and 5-HT2A receptors and displays partial agonist actions at 5-HT1A, 5-HT2C, D3, and D4 receptors. Aripiprazole can be used for the research of schizophrenia and COVID19[1][2][3][4].
Manufacturer - Research Area	Infection; Inflammation/Immunology; Neurological Disease
Solubility	DMF: 50 mg/mL (ultrasonic)\|DMSO: ≥ 100 mg/mL
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling
Isoform	5-HT1 Receptor; 5-HT2 Receptor; D2 Receptor; D3 Receptor; D4 Receptor; mLAG-3; α-1 microglobulin
Clinical information	Launched

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HY-14546-10mM-safety-datasheet.pdf