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Necrostatin 2 (racemate)

Necrostatin 2 (racemate)

Item no.	HY-14622A-50mg
Manufacturer	MedChem Express
CASRN	852391-15-2
Amount	50 mg
Quantity options	10 mM/1 mL 10 mg 1 mg 50 mg 5 mg
Category	Neuroscience Neuroinflammation Metabolism Diabetes Glucose Homeostasis Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.65
Citations	[1]Takahashi N, et al. Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models. Cell Death Dis. 2012 Nov 29;3:e437.
Smiles	ClC1=C2C(C(CC3C(N(C)C(N3)=O)=O)=CN2)=CC=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Necrostatin 1S,Nec-1S,7-Cl-O-Nec1
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	RIP kinase
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	277.71
Product Description	Necrostatin 2 racemate (Nec-1S), the Necrostatin-1 (HY-15760) stable, is a potent and specific RIPK1 inhibitor lacking the IDO-targeting effect[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO: ≥ 50 mg/mL
Manufacturer - Pathway	Apoptosis
Isoform	RIPK1
Clinical information	No Development Reported

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HY-14622A-50mg-safety-datasheet.pdf